New Flu Vaccine
How the “regular” flu shot is made
FDA advisory panel is entrusted with the task of selecting the three influenza strains which are thought to be in circulation for the time-span of the upcoming flu season and this process of selection is accomplished in each january at the middle of January and March.
However, assuming the whole process as an “educated guess,” CDC gets into the job of sending the selected seed virus to the FDA in order to have the approval which is truly prior to distributing the viruses to the manufacturers for production.
It is three separate strains that make the annual flu shot and to name those, these are two influenza A strains and one strain of influenza B. Moreover, herein lies a interesting factor to denote that two of the strains are those same viruses which, had been in the list of the preceding year’s shot.
To talk about the third new strain, it is selected each year and then gets into the modification process in the lab before it is added to the new seasonal shot.
New Cell Lines…are they really new?
Well, if we talk about the new technology, it is undoubtedly in its experimental process but in spite of this fact, it has been able to draw all major players in the vaccine industry into the craving process of a development of cell culture technology for flu shots. This new technological aspect was first brought into consideration and was described in the mid-1990s. one of its advantages is that the government can expand this methodology they desire to do so at the time of emergency.
When we talk about cell-culture technology, it has to mentioned that it is, by no means, new, though, it is absolutely new for flu shots. 1950 is the period when it was brought into use for the production of polio, measles, mumps and tetanus vaccines.
There are, in fact, some reasons for which the Cell-line technology was not used for flu shots. As for instance we can say that it requires complete retooling of production facilities prevalent at that time. The actual scenario was that the manufacturers were not too eager to invest the hundreds of millions of dollars and also was very time consuming factor.
But, pandemic possessed a threat for that and as a result of which the government decided to provide tens of billions of dollars to produce a bird flu vaccine. Once this process started, the manufacturers had a rapid proceed.
Flu Cell Culture Technology: The Next Frontier Overview
“Flu cell culture” is nothig but a term that refers to influenza vaccines derived from cell culture. The vaccines we are atlking about are made not from chicken eggs but from animal cells. This is unique in another aspect as it enables batches of vaccine to be produced taking not even six weeks.
Novartis flu cell line, which is also known as Madin-Darby (MDCK), has been found from the kidneys of a healthy female cocker spaniel. However, “immortalized cells” are perpetually divided cells and Solvay Pharmaceuticals, a Dutch company, has been in that project since the early 1990s.